Buspirone in detoxification

Apneusis responding to buspirone in multiple sclerosis.

Apneusis is a disturbance of respiratory rhythm characterized by severely prolonged inspiratory effort, and is caused by bilateral lesions in the dorsal pons. In humans it is most commonly caused by pontine infarction and has rarely been reported in multiple sclerosis (MS). Here we report on a patient with MS who developed episodic apneusis which responded to treatment with buspirone, a seroton...

Buspirone Hydrochloride 7-5mg

Buspirone hydrochloride is supplied as tablets for oral administration containing 5 mg, 7.5 mg, 10 mg or 15 mg of buspirone hydrochloride USP. The 5 mg and 10 mg tablets are scored so they can be bisected. Thus, the 5 mg tablet can also provide a 2.5 mg dose, and the 10 mg tablet can provide a 5 mg dose. The 15 mg tablet is scored so it can be either bisected or trisected. Thus, a single tablet...

6-OH Buspirone is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-HT1A Receptor Occupancy in Rats

Clonidine in Opiate Detoxification

Detoxification, the initial step in the treatment of opiate dependence (Freedman, 1980) has been facing difficulties in our country as the widely used drug methadone is not available. Earlier practices were either abrupt withdrawal or gradual tapering of the dose of the opiate to which the individual was dependent. Recently clonidine has been used with success for detoxification and treatment o...

Repurposing buspirone for drug addiction treatment.

Bernard Le Foll and Isabelle Boileau 1 Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada 2 Alcohol Research and Treatment Clinic, Addictions Program, CAMH, Toronto, Ontario, Canada 3 Departments of Psychiatry, Pharmacology, Family and Community Medicine and Institute of Medical S...